Overview
The VDRL test detects antibodies associated with syphilis activity. It is often used for screening and follow-up, but reactive results may need confirmatory treponemal testing.
What it detects
Nontreponemal antibodies associated with syphilis.
Sample type
Blood sample.
When it may be appropriate
Syphilis screening, diagnosis support and follow-up.
Window period considerations
May take several weeks after infection to become positive.
Test limitations
False positives can occur with other conditions; does not distinguish past treated infection by itself.
Interpretation basics
Reactive results usually need confirmatory testing; titers can help monitor treatment.
Follow-up recommendations
Confirm with treponemal test and assess symptoms and treatment history.
Key points
- Nontreponemal screening
- Useful for follow-up titers
- May have false positives
- Does not confirm alone
When to seek care
- Syphilis screening
- Follow-up after treatment
- Ulcer or rash evaluation