Overview

The RPR test is a nontreponemal blood test for syphilis. Like VDRL, it can be used for screening and monitoring treatment response.

What it detects

Nontreponemal antibodies associated with syphilis.

Sample type

Blood sample.

When it may be appropriate

Syphilis screening, diagnosis support and follow-up.

Window period considerations

May take several weeks after infection to become positive.

Test limitations

False positives can occur; results must be interpreted with treponemal tests.

Interpretation basics

Reactive results need confirmation; titers help monitor response.

Follow-up recommendations

Confirm with treponemal test and plan stage-appropriate care.

Key points

  • Similar role to VDRL
  • Screening and titer monitoring
  • Needs confirmation
  • Timing affects sensitivity

When to seek care

  • Syphilis screening
  • Treatment follow-up
  • Partner evaluation