Overview

Mycoplasma genitalium management is challenging because resistance is common. Testing and treatment should be guided by local patterns and clinical context.

Treatment approach

Targeted NAAT testing and resistance-aware treatment.

Common management options

  • Antibiotic regimens chosen by clinician
  • Test-of-cure may be needed

Medical supervision

A clinician should manage treatment due to resistance concerns.

Partner considerations

Partner evaluation may be recommended.

Follow-up

Persistent symptoms need reassessment and possible resistance testing.

Resistance considerations

M. genitalium resistance is a significant issue; avoid self-medication.

Key points

  • Resistance affects treatment
  • Testing guides choices
  • May need test-of-cure
  • Partner care may help

When to seek care

  • Persistent urethritis
  • Negative standard STI tests
  • Partner diagnosis