Overview

Syphilis testing often begins with a screening test and may be followed by confirmatory testing. Interpretation depends on symptoms, prior treatment and the possibility of false-positive screening results.

Key points

  • Screening and confirmatory test guidance
  • Stage-related symptom review
  • Treatment history review
  • Follow-up serology planning

When to seek care

  • Genital ulcer or rash
  • Positive screening result
  • Partner diagnosed with syphilis
  • Routine STI panel