Overview

Nongonococcal urethritis is urethral inflammation not caused by gonorrhea. Chlamydia is a common cause, but other organisms or irritants may be responsible.

Causes and transmission

  • Chlamydia trachomatis is a leading cause.
  • Mycoplasma genitalium, Trichomonas and other factors may contribute.

How it is assessed

  • Urine or urethral swab NAAT and microscopy.
  • Gonorrhea testing helps distinguish NGU from gonococcal urethritis.

Management considerations

  • Antibiotic treatment depends on likely cause and resistance.
  • Persistent symptoms need reassessment.

Prevention

  • Condoms reduce STI risk.
  • Avoid urethral irritants.

Key points

  • Urethritis without gonorrhea
  • Chlamydia is common cause
  • May be caused by other organisms
  • Requires testing

When to seek care

  • Burning urination
  • Urethral discharge
  • Persistent symptoms after gonorrhea excluded