Overview

Granuloma inguinale is a rare bacterial STI caused by Klebsiella granulomatis. It causes progressive genital ulcers and requires prolonged treatment.

Causes and transmission

  • Transmitted through sexual contact.
  • Rare in many settings but important in differential diagnosis.

How it is assessed

  • Clinical examination plus specialized testing or biopsy where available.
  • Other ulcer causes should be excluded.

Management considerations

  • Prolonged antibiotic treatment under specialist supervision.
  • Follow-up until lesions resolve.

Prevention

  • Avoid contact with active lesions.
  • Prompt diagnosis reduces complications.

Key points

  • Rare cause of genital ulcers
  • Progressive lesion growth
  • Requires prolonged antibiotics
  • More common in tropical regions

When to seek care

  • Progressive genital ulcer
  • Non-healing sore
  • Travel or regional exposure history